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Categoría: Publications

Cellular and humoral functional responses after BNT162b2 mRNA vaccination differ longitudinally between naive and subjects recovered from COVID-19

COVID-19, PublicationsPor Carlos del Fresnoenero 11, 2022Deja un comentario

We have analyzed BNT162b2 vaccine-induced immune responses in naive subjects and individuals recovered from coronavirus disease 2019 (COVID-19), both soon after (14 days) and later after (almost 8 months) vaccination.

The Bacterial Mucosal Immunotherapy MV130 Protects Against SARS-CoV-2 Infection and Improves COVID-19 Vaccines Immunogenicity

COVID-19, PublicationsPor Carlos del Fresnonoviembre 18, 2021Deja un comentario

COVID-19-specific vaccines are efficient prophylactic weapons against SARS-CoV-2 virus.

SARS-CoV-2 IgG seropositivity in a cohort of 449 non-hospitalized individuals during Spanish COVID-19 lockdown

COVID-19, PublicationsPor Carlos del Fresnonoviembre 3, 2021Deja un comentario

The Coronavirus Disease of 2019 (COVID-19) pandemic caused by SARS-CoV-2 led the Spanish government to impose a national lockdown in an attempt to control the spread of the infection.

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The immune checkpoints storm in COVID-19: Role as severity markers at emergency department admission

COVID-19, PublicationsPor Carlos del Fresnooctubre 15, 2021Deja un comentario

No abstract available

Cancers

Soluble SIGLEC5: A New Prognosis Marker in Colorectal Cancer Patients

PublicationsPor Carlos del Fresnoagosto 15, 2021Deja un comentario

Colorectal cancer (CRC) is the second most deadly and third most commonly diagnosed cancer worldwide.

DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells

Publications, Trained ImmunityPor Carlos del Fresnomayo 15, 2021Deja un comentario

Conventional type 1 dendritic cells (cDC1s) are central to antitumor immunity and their presence in the tumor microenvironment associates with improved outcomes in patients with cancer.

COVID-19 vaccine candidates based on modified vaccinia virus Ankara expressing the SARS-CoV-2 spike induce robust T- and B-cell immune responses and full efficacy in mice

COVID-19, PublicationsPor Carlos del Fresnomarzo 7, 2021Deja un comentario

Vaccines against SARS-CoV-2, the causative agent of the COVID-19 pandemic, are urgently needed.

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Myeloid cells in sensing of tissue damage

Publications, Trained ImmunityPor Carlos del Fresnofebrero 8, 2021Deja un comentario

Myeloid cells are components of the innate immune system that represent the first line of defense.

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Sensing Tissue Damage by Myeloid C-Type Lectin Receptors

Publications, Trained ImmunityPor Carlos del Fresnoabril 29, 2020Deja un comentario

After both sterile and infectious insults, damage is inflicted on tissues leading to accidental or programmed cell death.

Clec2d Joins the Cell Death Sensor Ranks

Publications, Trained ImmunityPor Carlos del Fresnoenero 14, 2020Deja un comentario

Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and immunity.

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