Sensing Tissue Damage by Myeloid C-Type Lectin Receptors
After both sterile and infectious insults, damage is inflicted on tissues leading to accidental or programmed cell death.
Clec2d Joins the Cell Death Sensor Ranks
Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and immunity.
A Proposal for Nomenclature in Myeloid C-Type Lectin Receptors
Myeloid C-type lectin receptors (CLRs) comprise a family of receptors expressed by immune myeloid cells that share homologous C-type lectin domains.
cDC1s: New Orchestrators of Tissue Innate Immunity
Type-I conventional dendritic cells (cDC1s) are key in inducing adaptive immunity.
Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection
β-Glucan-induced trained immunity in myeloid cells leads to long-term protection against secondary infections.
DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment
Host injury triggers feedback mechanisms that limit tissue damage.
Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation
Myeloid C-type lectin receptors (CLRs) are important sensors of self and non-self that work in concert with other pattern recognition receptors (PRRs).
Dectin-1 embraces Candida glabrata
Dectin-1 embraces Candida glabrata. No abstract available.
Neutrophils acROSs the Enemy Lines
In this issue of Immunity, Warnatsch et al. (2017) describe how neutrophils measure their microbial opponents by differential shuttling of reactive oxygen species (ROS)
Candida albicans triggers a differential profile of microRNAs depending on its growing form
Candida albicans triggers a differential profile of microRNAs depending on its growing form. No abstract available.